| uur | terrein | thuisploeg | bezoeker |
| REEKS A | | | | |
| W22A1 | 10.20 | Koolskamp | AC 't Rozeke | KWB Don Bosco |
| W22A2 | 8.45 | Kerelsplein | FC Transilvania | Keukens Roberdo |
| W22A3 | 8.45 | St. Eloois-Winkel | Wivo Sport | De Krisnaldo's |
| W22A4 | 9.15 | Ruddervoorde | FC Ter Mote | FC 't Kloefke |
| W22A5 | 9.30 | Wingene | Blue Stars | KVK Denys |
| W22A6 | 10.20 | Cringhene | K2 United | RW Nieuwe Stee |
| REEKS B | | | | |
| W22B1 | 9.15 | Pittem | STM Sjotters | B-Volted United |
| W22B2 | 9.00 | Madonna | Transvaal | Sportief Izegem |
| W22B3 | 9.00 | Kachtem | VK Kachtem | FC De Koolmijn |
| W22B4 | 9.15 | Ledegem | VC Rollegem-Kapelle | DDT Veldegem |
| W22B5 | 9.00 | Koekelare | Dakw. Maekelberg | FC Metteboys |
| W22B6 | 8.45 | Cringhene | VPA Sleihage | SV Werken |
| REEKS C | | | | |
| W22C1 | 8.45 | Koolskamp | FC Allemanshotters | FC 't Motje |
| W22C2 | 8.45 | Kortemark | FC 't Schaek | FC Den Tram |
| W22C3 | 8.45 | Rumbeke | Turbo's | VK Zwarte Gat |
| W22C4 | 8.45 | Moorslede | FC QVH | FC No Surrender |
| W22C5 | 9.00 | Merkem | Merkem Sport | FC Sherry's Pub |
| W22C6 | 8.45 | Dadizele | FC Aditco | Scoutaboe |