27 februari 2022
| uur | terrein | thuisploeg | bezoeker | |
|---|---|---|---|---|
| reeks A | ||||
| W22A1 | 09:15 | Zwevezele | Keuken Roberdo | RW Nieuwe Stee |
| W22A2 | 09:30 | Lichtervelde | VK Denys | De Krisnaldo's |
| W22A3 | 09:15 | Veldegem | DDT Veldegem | Devolder Sport |
| W22A4 | 09:30 | Handzame | FC De Geite | Geel Zwart Tube |
| W22A5 | 08:45 | St. Eloois-Winkel | Wivo Sport | Blue Stars |
| W22A6 | 09:00 | Cringhene | K2 United | FC Ter Mote |
| W22A7 | 08:45 | Ingelmunster | White-Red | FC Cera |
| reeks B | ||||
| W22B1 | 08:45 | Ledegem | VC Rollegem-Kapelle | Sportief Izegem |
| W22B2 | 08:45 | Staden | FC 't Kloefke | VPA Sleihage |
| W22B3 | 09:30 | Koekelare | Dakwerken Maekelberg | Re-Act |
| W22B4 | 09:00 | Madonna | Transvaal | KWB Don Bosco |
| W22B5 | 09:15 | Pittem | STM Sjotters | AC 't Rozeke |
| W22B6 | 08:45 | De Ark | FC Transilvania | FC Metteboys |
| W22B7 | 10:20 | Kortemark | SV Werken | Jong CD&V W-Dress |
| reeks C | ||||
| W22C1 | 09:00 | Kachtem | VK Kachtem | FC De Koolmijn |
| W22C2 | 08:45 | Cera | FC Allemanshotters | FC 't Motje |
| W22C3 | 09:15 | Dominiek Savio | FC No Surrender | Scoutaboe |
| W22C4 | 09:00 | Cera | Turbo's | Merkem Sport |
| W22C5 | 09:15 | Woumen | SV Woumen | VK Zwarte Gat |
| W22C6 | 10:20 | De Ark | FC Aditco | FC 't Lepelke |
| W22C7 | 08:45 | Kortemark | FC 't Schaek | FC Boomerang |