7 februari 2021
| uur | terrein | thuisploeg | bezoeker | |
|---|---|---|---|---|
| A | ||||
| W19A1 | 08:45 | Ingelmunster | Devolder Sport | RW Nieuwe Stee |
| W19A2 | 08:45 | St. Eloois-Winkel | Wivo Sport | FC Cera |
| W19A3 | 09:15 | Ruddervoorde | FC Ter Mote | DDT Veldegem |
| W19A4 | 9:30 | Cera | De Krisnaldo's | White-Red |
| W19A5 | 08:45 | Rumbeke | Geel Zwart Tube | Blue Stars |
| W19A6 | 09:30 | Handzame | FC De Geite | VK Denys |
| W19A7 | BYE | Keuken Roberdo | ||
| B | ||||
| W19B1 | 09:30 | Lichtervelde | Jong CD&V W-Dress | Dakwerken Maekelberg |
| W19B2 | 09:00 | Wijnendale | KWB Don Bosco | VC Rollegem-Kapelle |
| W19B3 | 08:45 | Cringhene | VPA Sleihage | FC Transilvania |
| W19B4 | 09:00 | Emelgem | Sportief Izegem | AC 't Rozeke |
| W19B5 | 08:45 | Staden | FC 't Kloefke | STM Sjotters |
| W19B6 | 08:45 | Kerelsplein | Re-Act | K2 United |
| W19B7 | BYE | FC Metteboys | ||
| C | ||||
| W19C1 | 08:45 | Cera | FC Allemanshotters | Turbo's |
| W19C2 | 09:15 | Woumen | SV Woumen | Scoutaboe |
| W19C3 | 09:00 | Madonna | Transvaal | FC De Koolmijn |
| W19C4 | 10:10 | Kerelsplein | FC Aditco | VK Zwarte Gat |
| W19C5 | 08:45 | Kortemark | FC 't Schaek | SV Werken |
| W19C6 | 09:30 | Merkem | Merkem Sport | FC 't Lepelke |
| W19C7 | 09:00 | Kachtem | VK Kachtem | FC Boomerang |