| uur | terrein | thuisploeg | bezoeker | | | |
| REEKS A | | | | | | | |
| W22A1 | 9.15 | Zwevezele | Keukens Roberdo | KWB Don Bosco | | - | |
| W22A2 | 9.00 | Koekelare | Dakw. Maekelberg | FC Ter Mote | | - | |
| W22A3 | 8.45 | St. Eloois-Winkel | Wivo Sport | FC 't Kloefke | | - | |
| W22A4 | 9.30 | Wingene | Blue Stars | B-Volted United | | - | |
| W22A5 | 9.30 | Lichtervelde | KVK Denys | FC Transilvania | | - | |
| W22A6 | 9.00 | Cringhene | K2 United | FC Metteboys | | - | |
| REEKS B | | | | | | | |
| W22B1 | 9.00 | Emelgem | Sportief Izegem | SV Werken | | - | |
| W22B2 | 8.45 | Zoete Pinte | FC Sherry's Pub | VPA Sleihage | | - | |
| W22B3 | 9.15 | Poelkapelle | FC De Koolmijn | De Krisnaldo's | | - | |
| W22B4 | 9.00 | Merkem | Merkem Sport A | VC Rollegem-Kapelle | | - | |
| W22B5 | 9.00 | Kachtem | VK Kachtem | FC No Surrender | | - | |
| W22B6 | 10.20 | Rumbeke | FC 't Motje | FC Den Tram | | - | |
| | | BYE | STM Sjotters | | - | |
| REEKS C | | | | | | | |
| W22C1 | 9.00 | Merkem | Merkem Sport B | FC QVH | | - | |
| W22C2 | 10.20 | Zoete Pinte | FC De Bassinboys | AC Alleman 't Rozeke | | - | |
| W22C3 | 10.20 | Dominiek Savio | Dynamo Bovekerke | FC Mascotte | | - | |
| W22C4 | 8.45 | Dominiek Savio | VK Zwarte Gat | FC Van Djiste Minute | | - | |
| W22C5 | 8.45 | Kortemark | FC 't Schaek | FC Scorpio | | - | |
| W22C6 | 8.45 | Rumbeke | Turbo's | RW Rood Wit | | - | |
| W22C7 | 8.45 | De Ruiter | No Limits | Scoutaboe | | - | |