| uur | terrein | thuisploeg | bezoeker |
| REEKS A | | | | |
| W21A1 | 8.45 | Kerelsplein | FC Transilvania | KWB Don Bosco |
| W21A2 | 9.30 | Lichtervelde | KVK Denys | K2 United |
| W21A3 | 9.00 | Staden | FC 't Kloefke | Blue Stars |
| W21A4 | 9.15 | Cringhene | De Krisnaldo's | FC Ter Mote |
| W21A5 | 9.15 | Zwevezele | Keukens Roberdo | Wivo Sport |
| W21A6 | 9.00 | Jonkershove | RW Nieuwe Stee | AC 't Rozeke |
| REEKS B | | | | |
| W21B1 | 9.00 | Dadizele | B-Volted United | Transvaal |
| W21B2 | 9.15 | Wevelgem | FC Metteboys | VPA Sleihage |
| W21B3 | 9.00 | Koekelare | Dakw. Maekelberg | VC Rollegem-Kapelle |
| W21B4 | 9.15 | Poelkapelle | FC De Koolmijn | DDT Veldegem |
| W21B5 | 9.00 | Emelgem | Sportief Izegem | VK Kachtem |
| W21B6 | 8.45 | Kortemark | SV Werken | STM Sjotters |
| REEKS C | | | | |
| W21C1 | 10.00 | Rumbeke | FC 't Motje | FC 't Schaek |
| W21C2 | 10.20 | Kerelsplein | FC Sherry's Pub | FC Aditco |
| W21C3 | 8.45 | Moorslede | FC QVH | Merkem Sport |
| W21C4 | 9.15 | Dominiek Savio | FC No Surrender | Turbo's |
| W21C5 | 9.30 | Oostnieuwkerke | FC Den Tram | VK Zwarte Gat |
| W21C6 | 10.20 | Kortemark | Scoutaboe | FC Allemanshotters |