31 januari 2021
| uur | terrein | thuisploeg | bezoeker | |
|---|---|---|---|---|
| A | ||||
| W18A1 | 09:15 | Veldegem | DDT Veldegem | Devolder Sport |
| W18A2 | 09:15 | Cera | FC Cera | FC Ter Mote |
| W18A3 | 09:15 | Zwevezele | Keuken Roberdo | Wivo Sport |
| W18A4 | 09:00 | Jonkershove | RW Nieuwe Stee | De Krisnaldo's |
| W18A5 | 08:45 | Rumbeke | Geel Zwart Tube | VK Denys |
| W18A6 | 08:45 | Ingelmunster | White-Red | Blue Stars |
| W18A7 | BYE | FC De Geite | ||
| B | ||||
| W18B1 | 09:15 | Wevelgem | FC Metteboys | VPA Sleihage |
| W18B2 | 08:45 | Ledegem | VC Rollegem-Kapelle | FC Transilvania |
| W18B3 | 09:30 | Lichtervelde | Jong CD&V W-Dress | KWB Don Bosco |
| W18B4 | 09:00 | Cringhene | K2 United | Dakwerken Maekelberg |
| W18B5 | 09:15 | Pittem | STM Sjotters | Re-Act |
| W18B6 | 09:15 | Koolskamp | AC 't Rozeke | FC 't Kloefke |
| W18B7 | BYE | Sportief Izegem | ||
| C | ||||
| W18C1 | 09:15 | Poelkapelle | FC De Koolmijn | FC Allemanshotters |
| W18C2 | 09:00 | Madonna | Transvaal | SV Woumen |
| W18C3 | 09:00 | Kachtem | VK Kachtem | Scoutaboe |
| W18C4 | 10:10 | Kerelsplein | FC 't Lepelke | FC Boomerang |
| W18C5 | 09:30 | Kortemark | SV Werken | Merkem Sport |
| W18C6 | 08:45 | Kerelsplein | FC Aditco | FC 't Schaek |
| W18C7 | 08:45 | Cera | Turbo's | VK Zwarte Gat |