9 januari 2022
| uur | terrein | thuisploeg | bezoeker | |
|---|---|---|---|---|
| reeks A | ||||
| W15A1 | 08:45 | St. Eloois-Winkel | Wivo Sport | Geel Zwart Tube |
| W15A2 | 08:45 | Ingelmunster | Devolder Sport | FC Ter Mote |
| W15A3 | 09:15 | Cera | De Krisnaldo's | FC Cera |
| W15A4 | 09:30 | Lichtervelde | VK Denys | RW Nieuwe Stee |
| W15A5 | 09:15 | Veldegem | DDT Veldegem | White-Red |
| W15A6 | 09:30 | Handzame | FC De Geite | K2 United |
| W15A7 | 09:30 | Wingene | Blue Stars | Keuken Roberdo |
| reeks B | ||||
| W15B1 | 09:00 | Wijnendale | KWB Don Bosco | AC 't Rozeke |
| W15B2 | 08:45 | Kerelsplein | Re-Act | FC Metteboys |
| W15B3 | 08:45 | Staden | FC 't Kloefke | Jong CD&V W-Dress |
| W15B4 | 08:45 | Cringhene | VPA Sleihage | Sportief Izegem |
| W15B5 | 09:30 | Koekelare | Dakwerken Maekelberg | SV Werken |
| W15B6 | 10:20 | De Ark | FC Transilvania | Transvaal |
| W15B7 | 09:15 | Pittem | STM Sjotters | VC Rollegem-Kapelle |
| reeks C | ||||
| W15C1 | 09:30 | Merkem | Merkem Sport | SV Woumen |
| W15C2 | 08:45 | Kortemark | Scoutaboe | FC 't Lepelke |
| W15C3 | 08:45 | Cera | FC Allemanshotters | FC Boomerang |
| W15C4 | 10:00 | Rumbeke | FC 't Motje | FC De Koolmijn |
| W15C5 | 10:20 | Kortemark | FC 't Schaek | FC No Surrender |
| W15C6 | 10:20 | Cera | Turbo's | FC Aditco |
| W15C7 | 09:30 | Dominiek Savio | VK Zwarte Gat | VK Kachtem |