10 oktober 2021
| uur | terrein | thuisploeg | bezoeker | |
|---|---|---|---|---|
| reeks A | ||||
| W5A1 | 09:00 | Jonkershove | RW Nieuwe Stee | Wivo Sport |
| W5A2 | 09:15 | Cera | FC Cera | FC Ter Mote |
| W5A3 | 09:15 | Zwevezele | Keuken Roberdo | DDT Veldegem |
| W5A4 | 09:30 | Handzame | FC De Geite | VK Denys |
| W5A5 | 09:30 | Wingene | Blue Stars | De Krisnaldo's |
| W5A6 | 09:00 | Cringhene | K2 United | Devolder Sport |
| W5A7 | 08:45 | Ingelmunster | White-Red | Geel Zwart Tube |
| reeks B | ||||
| W5B1 | 09:00 | Emelgem | Sportief Izegem | AC 't Rozeke |
| W5B2 | 09:30 | Lichtervelde | Jong CD&V W-Dress | FC Metteboys |
| W5B3 | 08:45 | Ledegem | VC Rollegem-Kapelle | Dakwerken Maekelberg |
| W5B4 | 09:00 | Madonna | Transvaal | VPA Sleihage |
| W5B5 | 09:15 | Pittem | STM Sjotters | FC 't Kloefke |
| W5B6 | 10:20 | De Ark | FC Transilvania | Re-Act |
| W5B7 | 10:20 | Kortemark | SV Werken | KWB Don Bosco |
| reeks C | ||||
| W5C1 | 09:15 | Poelkapelle | FC De Koolmijn | SV Woumen |
| W5C2 | 08:45 | Moorslede | FC 't Lepelke | FC Boomerang |
| W5C3 | 09:00 | Kachtem | VK Kachtem | FC No Surrender |
| W5C4 | 08:45 | Cera | Turbo's | FC 't Motje |
| W5C5 | 09:30 | Dominiek Savio | VK Zwarte Gat | FC Allemanshotters |
| W5C6 | 08:45 | De Ark | FC Aditco | Scoutaboe |
| W5C7 | 08:45 | Kortemark | FC 't Schaek | Merkem Sport |